Friday, August 8, 2025

GPT-5 🤖, Meta's TBD Lab 👨‍💻, GLP-1 pill 💊 

OpenAI has announced GPT-5 in three variants: GPT-5 Pro, GPT-5 mini, and GPT-5 nano. Some of the models will be available across all ChatGPT ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌  ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ 

TLDR

Together With Betterworks

TLDR 2025-08-08

🤖 AI Is Redefining the HR Tech Stack—and HR's Role With It (Sponsor)

In a live webinar next Thursday, Sapient Insights will share their latest research showing HR leaders aren't just supporting tech decisions—they're shaping them. From AI governance to workforce alignment, HR is playing a key role in enterprise tech strategy.

Join this exclusive webinar to discover:
– Where AI is reshaping HR systems (and what's next)
– How enterprise buyers are rethinking priorities and spend
– Why HR is becoming the backbone of tech ethics and governance

👉 Reserve your spot

📱

Big Tech & Startups

OpenAI launches GPT-5 free to all ChatGPT users (7 minute read)

OpenAI has announced GPT-5 in three variants: GPT-5 Pro, GPT-5 mini, and GPT-5 nano. Some of the models will be available across all ChatGPT, including for free users. OpenAI claims the new model family comes with reduced confabulations, improved coding capabilities, and a new approach to handling sensitive requests. Free users now have access to a simulated reasoning AI model. GPT-5 Pro is replacing o3-pro in ChatGPT for those subscriber tiers with access to it.
Meet TBD Lab, Meta's Superintelligence SWAT Team (5 minute read)

Meta's TBD Lab houses many of the researchers the company lured away from rival labs. It is spearheading Work on the newest version of Meta's large language model, Llama. The TBD Lab will work alongside Meta's other AI teams on a variety of projects. Meta has to date poached at least 18 researchers from OpenAI and a number from Google.
🚀

Science & Futuristic Technology

FDA approves breakthrough eye drops that fix near vision without glasses (6 minute read)

The US Food and Drug Administration has approved an eye drop that improves near vision in adults with presbyopia, a condition that causes near-sighted vision loss. The aceclidine-based eye drops offer relief from blurry near vision for up to 10 hours. They work by gently shrinking the pupil of the eye, creating a pinhole effect that helps bring nearby objects into sharper focus. The eyedrops do not significantly affect the eye's focusing muscles, so using them doesn't blur distance vision or cause myopic shift.
Eli Lilly Says Its New Weight-Loss Pill Is Highly Effective (5 minute read)

Eli Lilly has developed a new pill that causes obese people to lose significant amounts of weight. The drug targets GLP-1, potentially increasing access to GLP-1 medications due to price and ease of application. Its side effect profile is similar to that of the injectable GLP-1 drugs. Eli Lilly plans to file for approval for the drug by the end of the year.
💻

Programming, Design & Data Science

How ThreatSpike added up to $75K in pipeline per campaign with TLDR Newsletter ads (Sponsor)

ThreatSpike ditched underperforming channels like Google and LinkedIn for TLDR. The results?

  • Consistent $25K to $75K in pipeline per campaign
  • High-intent leads from enterprise companies with 30K+ employees
  • Direct reach to decision-makers actively looking for solutions<

We break down ThreatSpike's exact strategy, share their results, and reveal the ads that drove performance.

Read the ThreatSpike case study.

GPT-5 (13 minute read)

GPT-5 rarely screws up and generally feels competent. The model used in ChatGPT is a hybrid that switches between different models. GPT-5 is available as three models in the API: regular, mini, and nano. Each can be run at one of four reasoning levels. This post looks at the key characteristics of the models, how they are priced, and what can be learned from the GPT-5 system card.
Built With Borrowed Hands (14 minute read)

Ignore the claims about vibe coding or that you don't need to know how to write code, and instead look for ways to augment what you do. Experiment with AI and discover what value you can extract - there's a lot of grift. Learn for yourself what works and what doesn't. AI in its current form won't ever replace hands-on-keyboards, and it won't replace engineering.
🎁

Miscellaneous

The Next Parenting Trend Starts Before Conception (132 minute read)

Orchid is a company that lets parents genetically test embryos before pregnancy. Parents can choose their future baby for as little as $2,500. This article features a transcript of an interview with the company's founder, where they debate the scientific, moral, and ethical implications of designing a 'healthy' child and what we lose in separating reproduction from sex. With Orchid's technology, parents in the future will not have to roll the dice with their child's health.
Intel's CEO, Under Attack From Trump, Is Already at Odds With His Board (7 minute read)

Intel's Chief Executive Lip-Bu Tan and some Intel directors disagree on topics as central as whether the company should stay in the manufacturing business or exit it entirely. Tan recently tried to raise new capital to acquire an artificial intelligence company, but efforts have been stalled by people on the board. Despite Trump unexpectedly calling for Tan's ouster, the company is so far standing by Tan, saying that the board and Tan are all deeply committed to advancing US national and economic security interests. While Intel's chip factories are a money loser, some view them as politically important because they help secure the US semiconductor supply chain.

Quick Links

High costs and thin margins threatening AI coding startups (6 minute read)

AI coding assistants can actually be massively money-losing businesses.
Cursor CLI (Website)

Cursor CLI lets developers interact with AI agents directly from their terminal to write, review, and modify code.
Tesla Disbands Dojo Supercomputer Team in Blow to AI Effort (5 minute read)

Tesla's Dojo team has lost 20 workers to a recently formed startup, - remaining Dojo workers will be reassigned to other data center and compute projects within Tesla.
Amazon's Zoox Taxi Is Clear To Operate Without A Steering Wheel Or Pedals (3 minute read)

The National Highway Traffic Safety Administration has cleared Zoox to deploy its fleet of steering wheel-less electric pods for demonstration purposes.
Linear sent me down a local-first rabbit hole (10 minute read)

The user experience benefits of local-first are undeniable.
How AI Conquered the US Economy: A Visual FAQ (8 minute read)

The American economy has split into a rip-roaring AI economy and a lackluster consumer economy.

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Thanks for reading,
Dan Ni & Stephen Flanders


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